Juan M Benito Selected Research

Camptothecin

1/2023	Insight into oral amphiphilic cyclodextrin nanoparticles for colorectal cancer: comprehensive mathematical model of drug release kinetic studies and antitumoral efficacy in 3D spheroid colon tumors.
12/2021	Therapeutic efficacy and gastrointestinal biodistribution of polycationic nanoparticles for oral camptothecin delivery in early and late-stage colorectal tumor-bearing animal model.
6/2020	Cyclodextrin nanoparticle bound oral camptothecin for colorectal cancer: Formulation development and optimization.

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Juan M Benito Research Topics

Disease

8	Neoplasms (Cancer) 01/2023 - 10/2016
4	Gaucher Disease (Gaucher's Disease) 01/2017 - 06/2011
3	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 06/2020
2	Breast Neoplasms (Breast Cancer) 01/2017 - 10/2016
1	Colonic Neoplasms (Colon Cancer) 01/2023
1	Carcinoma (Carcinomatosis) 01/2023
1	Neoplasm Metastasis (Metastasis) 12/2021
1	Cardiotoxicity 02/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021
1	Liver Neoplasms (Liver Cancer) 01/2021
1	Conjoined Twins (Siamese Twins) 07/2019
1	Peritoneal Neoplasms 10/2017
1	Ascites 10/2017
1	Edema (Dropsy) 01/2011

Drug/Important Bio-Agent (IBA)

9	CyclodextrinsIBA 01/2023 - 04/2014
3	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 01/2023 - 06/2020
3	CamptothecinIBA 01/2023 - 06/2020
3	SolutionsIBA 12/2021 - 01/2017
3	Glucosylceramidase (Glucocerebrosidase)IBA 01/2017 - 06/2011
2	Paclitaxel (Taxol)FDA LinkGeneric 02/2021 - 01/2017
2	CholesterolIBA 01/2021 - 10/2016
2	AcidsIBA 04/2014 - 06/2011
2	Glucosylceramides (Glucocerebrosides)IBA 04/2014 - 06/2011
2	GlucosidasesIBA 04/2014 - 06/2011
1	MucinsIBA 01/2023
1	Antimitotic AgentsIBA 02/2021
1	NanocapsulesIBA 01/2021
1	Tyrosine Kinase InhibitorsIBA 01/2021
1	Therapeutic UsesIBA 01/2021
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2021
1	DNA (Deoxyribonucleic Acid)IBA 07/2019
1	DisaccharidesIBA 07/2019
1	Surface-Active Agents (Surfactants)IBA 07/2019
1	Tyr sulfate(1)- enkephalinamide-Leu (LETS)IBA 07/2019
1	TrehaloseIBA 07/2019
1	Small Interfering RNA (siRNA)IBA 10/2017
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 01/2017
1	NucleotidesIBA 01/2017
1	5- N,6- O- (N''- octyliminomethylidene)nojirimycinIBA 06/2011
1	EnzymesIBA 06/2011
1	nojirimycinIBA 06/2011
1	Proteins (Proteins, Gene)FDA Link 06/2011
1	anthrax toxin (anthrax lethal factor)IBA 01/2011
1	AntigensIBA 01/2011

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 01/2023 - 10/2017
2	Therapeutics 10/2016 - 06/2011
1	Oral Administration 01/2023
1	Nanospheres 01/2021
1	Cytoreduction Surgical Procedures 10/2017